Keselamatan dari Toyota Fortuner adalah sebagai berikut:
| Varian | Toyota Fortuner 2.4 G MT | Toyota Fortuner 2.4 G AT | Toyota Fortuner 2.4 VRZ AT | Toyota Fortuner 2.4 TRD AT | Toyota Fortuner 2.4 G AT 4x4 | Toyota Fortuner 2.4 VRZ AT 4x4 | Toyota Fortuner 2.7 SRZ AT | Toyota Fortuner 2.7 TRD AT |
| Peringkat Euro NCAP | ||||||||
| Peringkat ASEAN NCAP | ||||||||
| Jumlah airbag | ||||||||
| Airbag kursi penumpang / utama | ||||||||
| Airbag sisi depan / belakang | ||||||||
| Airbag lutut | ||||||||
| Pengingat sabuk pengaman | ||||||||
| Active emergency braking system | ||||||||
| Tire Pressure Monitoring System (TPMS) | N | N | N | N | N | N | N | N |
| Lane Departure Warning System (LDWS) | ||||||||
| Lane Keeping Assist System (LKAS) | ||||||||
| Collision avoidance system(CAS) | ||||||||
| Anti-lock Braking System (ABS) | ||||||||
| Electronic Brake-force Distribution (EBD) | Y | Y | Y | Y | Y | Y | Y | Y |
| Sistem kontrol traksi | ||||||||
| Vehicle Stability Control (VSC) | ||||||||
| Child safety lock | Y | Y | Y | Y | Y | Y | Y | Y |
| ISOFIX | ||||||||
| Security alert | ||||||||
| Immobilizer | Y | Y | Y | Y | Y | Y | Y | Y |
