Keselamatan dari Daihatsu Grand Xenia adalah sebagai berikut:
| Varian | Daihatsu Grand Xenia 1.3 X MT | Daihatsu Grand Xenia 1.3 R MT | Daihatsu Grand Xenia 1.3 X AT | Daihatsu Grand Xenia 1.3 X Deluxe MT | Daihatsu Grand Xenia 1.3 R AT | Daihatsu Grand Xenia 1.3 R Deluxe MT | Daihatsu Grand Xenia 1.3 X Deluxe AT | Daihatsu Grand Xenia 1.5 R Deluxe MT | Daihatsu Grand Xenia 1.3 R Deluxe AT | Daihatsu Grand Xenia 1.5 R Deluxe AT |
| Peringkat Euro NCAP | ||||||||||
| Peringkat ASEAN NCAP | ||||||||||
| Jumlah airbag | ||||||||||
| Airbag kursi penumpang / utama | ||||||||||
| Airbag sisi depan / belakang | ||||||||||
| Airbag lutut | ||||||||||
| Pengingat sabuk pengaman | ||||||||||
| Active emergency braking system | ||||||||||
| Tire Pressure Monitoring System (TPMS) | N | N | N | N | N | N | N | N | N | N |
| Lane Departure Warning System (LDWS) | ||||||||||
| Lane Keeping Assist System (LKAS) | ||||||||||
| Collision avoidance system(CAS) | ||||||||||
| Anti-lock Braking System (ABS) | ||||||||||
| Electronic Brake-force Distribution (EBD) | N | N | N | N | N | N | N | Y | N | Y |
| Sistem kontrol traksi | ||||||||||
| Vehicle Stability Control (VSC) | ||||||||||
| Child safety lock | Y | Y | Y | Y | Y | Y | Y | Y | Y | Y |
| ISOFIX | ||||||||||
| Security alert | ||||||||||
| Immobilizer | Y | Y | Y | Y | Y | Y |
