Kenyamanan dari Mercedes-Benz GLC-Class adalah sebagai berikut:
| Varian | Mercedes-Benz GLC-Class 200 Exclusive Line | Mercedes-Benz GLC-Class 200 AMG Line | Mercedes-Benz GLC-Class 300 Coupe 4MATIC AMG Line | Mercedes-Benz GLC-Class AMG 43 4MATIC Coupe |
| Sensor parkir depan | ||||
| Sensor parkir belakang | ||||
| Driving assistance image | Y | Y | Y | Y |
| Cruise system | Y | Y | Y | Y |
| Parkir otomatis | ||||
| Start/Stop engine button | Y | Y | Y | Y |
| Hill Start Assist (HSA) | ||||
| Hill Descent Control (HDC) | ||||
| Pengatur Moda Berkendara | ||||
| limited-slip differential (LSD) | ||||
| Differential lock | ||||
| Headlight height adjustment |
